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Goltsov Sergey
I serve the art of medical doubt

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Buffalo. History of the creation of the custom motorcycle


Day in day, exactly 5 years, in Mikhail Sharomov's custom workshop, we created this unique custom motorcycle named Buffalo with Harley Davidson V-ROD engine. From idea and concept, design and implementation in every technical detail, through years of friendship, creation and inspired creativity to final assembly and registration. About that in my short film "Buffalo".

PHENOTYPIC DERMATOLOGY IN THE LIGHT OF THE POSSIBILITIES OF GENUS-STRUCTURAL EXPLICATION OF MEMBRANE EVENTS ON THE SURFACE OF HUMAN SKIN CELLS
PHENOTYPIC DERMATOLOGY IN THE LIGHT OF THE POSSIBILITIES OF GENUS-STRUCTURAL EXPLICATION OF MEMBRANE EVENTS ON THE SURFACE OF HUMAN SKIN CELLS

The method of conceptual analysis substantiates a variety of states of skin cell subpopulations, which opens up a whole class of research tasks for studying cell phenotypes and further enhancing knowledge about the etiology and pathogenesis of skin diseases... read more

Болезни кожи. Атлас.
Болезни кожи. Атлас.

В 2014 году мне посчастливилось принять участие в создании атласа болезней кожи. Это упоительно быть частью большого и высокопрофессионального коллектива авторов, многие из которых были моими наставниками, а большинство остаются добрыми коллегами. полистать...

Matrix GO for clinic management
Matrix GO for clinic management
Conceptualization of human skin cell subpopulation states
Conceptualization of human skin cell subpopulation states

The results of several patented inventions investigate the dynamics of human skin cell subpopulation states. The immunological phenomena discovered thereby change not only the picture of skin conditions, but also the ideas about approaches to the diagnosis and treatment of skin diseases... read the article in full

CYTOIMMUNOGRAM OF THE SKIN: A NEW METHOD FOR OBJECTIVE EVALUATION OF THE SKIN CELL SUBPOPULATION PROFILE
CYTOIMMUNOGRAM OF THE SKIN: A NEW METHOD FOR OBJECTIVE EVALUATION OF THE SKIN CELL SUBPOPULATION PROFILE

История дерматологии помнит массу попыток преобразовать кожу человека – плотную ткань в жидкость. Поиск способа разделения клеточного субстрата кожи для получения суспензии и изучения фенотипа клеток, входящих в ее состав, стал основой многолетнего исследования, результатом которого явился патентованный способ цифровой оценки субпопуляционного состава клеток кожи – цитоиммунограмма кожи... читать статью целиком

Features of the clinical course of the family form of myofibrillar desmin-dependent myopathy
Features of the clinical course of the family form of myofibrillar desmin-dependent myopathy

Desmopathy is a rare hereditary disease associated with a mutation in the DES gene, which is a kind of myofibrillar myopathy. With this disease, it is possible to damage skeletal, cardiac, smooth muscles, as well as diaphragm. In clinical practice, desminopathy is a difficult diagnostic task. In this article, the clinical case of the family form of myofibrillar myopathy with the established mutation c.1021A> C (Thr341Pro) in the DES gene in the heterozygous state is considered. We present a family study in a cumulative calculus of over 100 years describing the dynamics of clinical manifestations, morphological, cardiological and electromyographic parameters.

Key words: desmin, DES, desminopathy, myofibrillar myopathy, mutation, cancer, electromyography, heart failure

METHOD FOR DETERMINING SUBPOPULATION COMPOSITION OF SKIN CELLS AND OBTAINING SKIN CYTOIMMUNOGRAM
METHOD FOR DETERMINING SUBPOPULATION COMPOSITION OF SKIN CELLS AND OBTAINING SKIN CYTOIMMUNOGRAM

Application of this method allows to make a quantitative and functional characteristic of all the skin constituent elements for use in diagnosis.

Nature-Friendly Strategy for Growing Innovation: the Placental Approach
Nature-Friendly Strategy for Growing Innovation: the Placental Approach

The creation of fertile innovative ecological environment in the country is constrained by barriers of a conceptual nature. The article identifies four groups of such barriers. The authors propose a strategy for overcoming them based on a comparison of functions necessary for the innovative development of social practices and the natural mechanisms of a new life birth. This allows us to formulate a number of pragmatic recommendations for creating an innovative eco-environment for a wide range of industries. By analogy with natural dynamics of obstetrics, the approach is called placental

Keywords: Innovation, innovation infrastructure, acceleration, eco-environment, placenta, development.

THE FUNCTION OF ANTIAPOPTOSIS EFFECT OF HEALING REMEDI OF CELLGEL
THE FUNCTION OF ANTIAPOPTOSIS EFFECT OF HEALING REMEDI OF CELLGEL

Одним из перспективных направлений является применение новых технологий, в частности разработка препаратов, обладающих способностью к нейтрализации и элиминации патогенных микроорганизмов, хорошо проникающих в рану и обладающих репаративными свойствами... читать далее

CERTAIN IMMUNOPFYSIOLOGICAL MECHANISMS OF WOUND REPAIR IN CONDITION OF WOUND HEALING MADICAL MEANS «Cellgel» APPLICATION
CERTAIN IMMUNOPFYSIOLOGICAL MECHANISMS OF WOUND REPAIR IN CONDITION OF WOUND HEALING MADICAL MEANS «Cellgel» APPLICATION

Проведен эксперимент на 40 половозрелых кроликах с целью сравнения пролиферативной и апоптотической активности клеток эпидермиса и дермы при формировании грубого соединительнотканного рубца и эпителизации раны без образования рубца с восстановлением функции поврежденного участка... читать о результатах эксперимента

Phenotypic dermatology
Phenotypic dermatology

A quarter of a century ago, having begun my practice as a dermatologist, I remain to this day a zealous believer in the idea that medicine can only be personalized. It came to me very early on to understand the need to move from treating one patient to treating many through the creation of a methodology. Remembering the French singer Edith Piaf, who said: "I don't sing for everyone, I sing for everyone," while objectively she sang for everyone, I also remember well the inspiration I felt when I first thought of... 
phenotypic dermatology

Устройство для активации репаративных потенций клеток кожи
Устройство для активации репаративных потенций клеток кожи

Устройство для активации репаративных потенций клеток кожи... читать об устройстве

 

Training in a new fashion!

"Testing site", "a different approach to training", "a new level of the training process" –  this is how the students describe the training process in private establishment of continuing professional education for medical staff at. This is all about applying special approaches to the postgraduate education More...

 

Comparative evaluation of quality of hematopoietic stem cells of umbilical cord blood at various methods of cryopreservation
Comparative evaluation of quality of hematopoietic stem cells of umbilical cord blood at various methods of cryopreservation

Studied the proliferative potential and viability of hematopoietic stem cells (HSC) cord blood (PB), depending on the method of cryopreservation. Cryopreservation of samples was carried out in software Planer freezer and liquid nitrogen vapor. Found that, for cryopreservation of samples GSK PC software should be used freezer, since this method of preservation of the cells remain vi- able and functional completeness.

Регенераторно-репаративные и антибактериальные свойства препарата «CELLGEL» в эксперименте
Регенераторно-репаративные и антибактериальные свойства препарата «CELLGEL» в эксперименте

Необходимость в создании препаратов, обладающих одновременно антибактериальным и репаративным эффектом, остается актуальной... читать статью 

Способ получения жизнеспособной гетерогенной популяции клеток кожи
Способ получения жизнеспособной гетерогенной популяции клеток кожи
Wound healing with Cellgel
Wound healing with Cellgel

The ability to heal is the most important property of the skin, determining the tendency to close a wound or injury "at any cost. However, healing can be with or without scarring. So what is the secret?