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Goltsov Sergey
I serve the art of medical doubt

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Dermatology: from observation to understanding
Dermatology: from observation to understanding

The theory of phenotypic dermatology: technologies and research that are changing the understanding of the diagnosis and treatment of skin diseases.

Third book
Third book

Surprisingly, there are 14 years between these books. That's exactly how long Leo Tolstoy felt one cycle of human maturation constitutes. He had an almost intimate idea of ​​dividing life into periods—conditional periods in which, every fourteen years, a person reaches a new level of understanding.

If, putting aside excessive modesty (briefly and strictly for scientific purposes), we apply this logic to ourselves, a curious picture emerges.

The principle of Cellgel or how does Cellgel work?

Цельгель искусственно повышает концентрацию сигнальных молекул в ране, чтобы активировать механизмы репарации и ускорить естественные механизмы регенерации кожи, которые у человека с возрастом ослабевают. Покупайте в клинику, покупайте себе...

Biotechnological agent for therapy of skin lesions of various etiologies
Biotechnological agent for therapy of skin lesions of various etiologies

Taking into account the universality of the pathogenesis of the wound process and the existence of substances predictably affecting the nature of the immune response in the skin and certain functions of its constituent cells (including reparative), the development of a new biotechnological agent for healing skin wounds of different etiology is justified and relevant.

This determined the aim and objectives of this study. Read more...

Let's get acquainted
Let's get acquainted

A man can talk about anything, but he only talks about himself with pleasure. :)
+ my telegram channel "from observation to understanding"

Diseases of the skin. Atlas.
Diseases of the skin. Atlas.

In 2014, he participated in the creation of an atlas of skin diseases.

To leaf through...

founded in 2005
founded in 2005
Matrix GO for clinic management
Matrix GO for clinic management

The release of Matrix GO version Y with all the bells and whistles and compliance with all the requirements is already being actively implemented in clinics.number of pragmatic solutions for managing the clinic are offered. Do not wait for new requirements to take you by surprise!e!

Conceptualization of human skin cell subpopulation states
Conceptualization of human skin cell subpopulation states

The results of several patented inventions investigate the dynamics of human skin cell subpopulation states. The immunological phenomena discovered thereby change not only the picture of skin conditions, but also the ideas about approaches to the diagnosis and treatment of skin diseases... read the article in full

CYTOIMMUNOGRAM OF THE SKIN: A NEW METHOD FOR OBJECTIVE EVALUATION OF THE SKIN CELL SUBPOPULATION PROFILE
CYTOIMMUNOGRAM OF THE SKIN: A NEW METHOD FOR OBJECTIVE EVALUATION OF THE SKIN CELL SUBPOPULATION PROFILE

The history of dermatology remembers many attempts to transform human skin, a dense tissue, into a liquid. The search for a method to separate the skin's cellular substrate to obtain a suspension and study the phenotype of its constituent cells became the basis for a long-term research, resulting in a patented method for digitally assessing the subpopulation composition of skin cells - the skin cytoimmunogram... read the full article

METHOD FOR DETERMINING SUBPOPULATION COMPOSITION OF SKIN CELLS AND OBTAINING SKIN CYTOIMMUNOGRAM
METHOD FOR DETERMINING SUBPOPULATION COMPOSITION OF SKIN CELLS AND OBTAINING SKIN CYTOIMMUNOGRAM

Application of this method allows to make a quantitative and functional characteristic of all the skin constituent elements for use in diagnosis.

Nature-Friendly Strategy for Growing Innovation: the Placental Approach
Nature-Friendly Strategy for Growing Innovation: the Placental Approach

The creation of fertile innovative ecological environment in the country is constrained by barriers of a conceptual nature. The article identifies four groups of such barriers. The authors propose a strategy for overcoming them based on a comparison of functions necessary for the innovative development of social practices and the natural mechanisms of a new life birth. This allows us to formulate a number of pragmatic recommendations for creating an innovative eco-environment for a wide range of industries. By analogy with natural dynamics of obstetrics, the approach is called placental

Keywords: Innovation, innovation infrastructure, acceleration, eco-environment, placenta, development.

THE FUNCTION OF ANTIAPOPTOSIS EFFECT OF HEALING REMEDI OF CELLGEL
THE FUNCTION OF ANTIAPOPTOSIS EFFECT OF HEALING REMEDI OF CELLGEL

Одним из перспективных направлений является применение новых технологий, в частности разработка препаратов, обладающих способностью к нейтрализации и элиминации патогенных микроорганизмов, хорошо проникающих в рану и обладающих репаративными свойствами... читать далее

History of the dermatovenerological service of the Tyumen region
History of the dermatovenerological service of the Tyumen region

Information about the history of medical institutions Tyumen, which used to belong to the Tobolsk province, has been preserved a little. It is known that in 1741 there was a hospital in the city, which had 3 attendants. The hospital was located at the monastery. In the first half of the 19th century (1845), there was already one hospital in the city. There were 5 officials (doctors) and 7 lower attendants (orderlies) in the medical department. In 1859, the city hospital was opened, considered by contemporaries to be the best in Western Europe. Siberia, which has six hospital rooms, a laboratory, a pharmacy, and an anatomical theater... The whole story

CERTAIN IMMUNOPFYSIOLOGICAL MECHANISMS OF WOUND REPAIR IN CONDITION OF WOUND HEALING MADICAL MEANS «Cellgel» APPLICATION
CERTAIN IMMUNOPFYSIOLOGICAL MECHANISMS OF WOUND REPAIR IN CONDITION OF WOUND HEALING MADICAL MEANS «Cellgel» APPLICATION

Проведен эксперимент на 40 половозрелых кроликах с целью сравнения пролиферативной и апоптотической активности клеток эпидермиса и дермы при формировании грубого соединительнотканного рубца и эпителизации раны без образования рубца с восстановлением функции поврежденного участка... читать о результатах эксперимента

Phenotypic dermatology
Phenotypic dermatology

Quite early on, I realized that to truly help a large number of patients, I needed to go beyond the individual approach and create a methodology. I recall the words of Edith Piaf, who said, "I don't sing for everyone—I sing for everyone." And yet, she sang for everyone. So it was for me—there was that inspiration, that moment when the idea of ​​phenotypic dermatology first arose. It was from this moment that the path to a systemic view of the skin began—not as a surface, but as an entire biological universe.

A device for activating the reparative potencies of skin cells (utility model patent)
A device for activating the reparative potencies of skin cells (utility model patent)

A device for activating the reparative potencies of skin cells... read about the device

To be remembered and used
To be remembered and used

Skin and venereal diseases are among the oldest diseases of mankind that have accompanied humans at all stages of evolution. It is worth noting that the oldest example of medical literature, namely a clay tablet with a Sumerian text found in Nippur (in modern Iraq), tells about the treatment of skin diseases. After tens of thousands of years, I want to talk and write about skin and venereal diseases.

Comparative evaluation of quality of hematopoietic stem cells of umbilical cord blood at various methods of cryopreservation
Comparative evaluation of quality of hematopoietic stem cells of umbilical cord blood at various methods of cryopreservation

Studied the proliferative potential and viability of hematopoietic stem cells (HSC) cord blood (PB), depending on the method of cryopreservation. Cryopreservation of samples was carried out in software Planer freezer and liquid nitrogen vapor. Found that, for cryopreservation of samples GSK PC software should be used freezer, since this method of preservation of the cells remain vi- able and functional completeness.

Регенераторно-репаративные и антибактериальные свойства препарата «CELLGEL» в эксперименте
Регенераторно-репаративные и антибактериальные свойства препарата «CELLGEL» в эксперименте

Необходимость в создании препаратов, обладающих одновременно антибактериальным и репаративным эффектом, остается актуальной... читать статью 

Method for obtaining a viable heterogeneous population of skin cells (patent for invention)
Method for obtaining a viable heterogeneous population of skin cells (patent for invention)

The invention relates to the field of pharmaceuticals and biology and represents a method for obtaining a viable heterogeneous population of skin cells, which includes taking a skin biopsy at a depth of ...

Wound-healing Cellgel
Wound-healing Cellgel

The ability to repair is the most important property of the skin that determines the closure of a wound or injury "at all costs". However, healing can be with or without scarring. So what is the secret?